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Navajo Birth Cohort Study (NBCS)
Navajo Birth Cohort Study logo
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Sample details

The NCBS aims to better understand the relationship between uranium and environmental metal exposures with birth outcomes and children’s development on the Navajo Nation in the United States of America. From 2019, NCBS has been included in the Environmental influences on Child Health Outcomes (ECHO) program, allowing it to study a broader set of health outcomes that include obesity, upper and lower airway function, birth outcomes, neurodevelopment and overall health. Participants are around 1,000 mother-child dyads recruited while the women were pregnant from maternity health services in the Navajo Nation. Since 2013, pregnant women have completed a baseline assessment at enrolment, and their children have been assessed at birth, with annual follow-ups until the child is nine years old.

Study design
Cohort, Cohort - birth, Cohort - primary caregiver and child

Number of participants at first data collection

979 (mother-child dyads as of 2021)

Recruitment is ongoing

Age at first data collection

14 - 45 years (mothers)

Birth (children)

Participant year of birth

Varied (mothers)

2013 - 2025 (children)

Participant sex
All

Representative sample at baseline?
No

Sample features

Children and young people
Indigenous peoples
Mother and child dyad
Newborns, infants and babies
Pregnant people
Dataset details

Country

United States of America

Year of first data collection

2013

Primary Institutions

University of New Mexico (UNM)

Links

hsc.unm.edu/pharmacy/research/areas/nbcs-echo/

reporter.nih.gov/project-details/10908607

doi.org/10.1289/EHP10361

sric.org/nbcs/index.php

Funders

Centers for Disease Control and Prevention (CDC)

National Institutes of Health (NIH)

Ongoing?
Yes

Data types collected

mentalHealthData
dataLinkage
Quantitative data collection
  • Interview – face-to-face
  • Physical environment assessment (e.g. pollution, mould)
  • Physical or biological assessment (e.g. blood, saliva, gait, grip strength, anthropometry)
  • Secondary data
  • Self-report questionnaire – unspecified
Qualitative data collection
  • None
Neuroimaging data collection
  • None
Linked or secondary data
  • Healthcare data
  • Medical birth registry
Features

Engagement

  • Community engagement
  • Keywords

    Biological samples/biospecimens
    Developmental disorders and psychopathology
    Environmental exposures
    Heavy metals
    Human development
    Neurodevelopment
    Pregnancy
    Socioeconomics

    Consortia and dataset groups

    Environmental influences on Child Health Outcomes (ECHO)
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