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NeoLifeS
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Sample details

NeoLifeS is a prospective study investigating neurodevelopmental outcomes of preterm infants admitted to the neonatal intensive care unit (NICU) of the University Medical Center Groningen (UMCG) in the Netherlands. The cohort includes very preterm infants born before 30 weeks of gestation and/or with a birth weight of <1000 grams. As of 2025, around 400 infants born between May 2015 and July 2020 have been assessed at 3, 6, 12, and 24 months of age during routine follow-up appointments. The study aims to continue long-term follow-up into adolescence, assessing physical health, growth, and neurodevelopment (motor, cognitive, behavioural domains).

Study design
Cohort, Cohort - clinical, Cohort - birth

Number of participants at first data collection

399 (participants)

Recruitment is ongoing

Age at first data collection

Birth (participants)

Participant year of birth

2015 onwards (participants)

Participant sex
All

Representative sample at baseline?
A very preterm born population admitted to a Dutch tertiary neonatal intensive care unit (NICU) with regard to neonatal morbidity and mortality.

Sample features

Low birthweight infants
Newborns, infants and babies
Patients and clinical populations
Preterm infants
Dataset details

Country

Netherlands

Year of first data collection

2015

Primary Institutions

University Medical Center Groningen (Universitair Medisch Centrum Groningen, UMCG)

Links

umcgresearch.org/w/neolifes

umcgresearchdatacatalogue.nl/UMCG/ssr-catalogue/all/cohorts/NEOLIFES

doi.org/10.1016/j.ejpn.2021.03.014

doi.org/10.1016/j.earlhumdev.2021.105504

Funders

No funding information available

Ongoing?
Yes

Data types collected

neuroImagingData
mentalHealthData
dataLinkage
Quantitative data collection
  • Audio or visual recordings (e.g. of child behaviour, facial expressions)
  • Physical or biological assessment (e.g. blood, saliva, gait, grip strength, anthropometry)
  • Secondary data
  • Self-report questionnaire – paper or computer assisted
Qualitative data collection
  • None
Neuroimaging data collection
  • Near-infrared spectroscopy (NIRS)
Linked or secondary data
  • Healthcare data
  • Medical birth registry
Features

Engagement

  • None
  • Keywords

    Behaviour
    Biological samples/biospecimens
    Infant outcomes
    Lung health
    Maternal mental health
    Motor function
    Neurodevelopment
    Neuroimaging
    Paediatric development
    Premature birth
    Sub-studies
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