Nurses' Health Study II (NHS II)
The NHS II is the second in a series of large prospective cohort studies aimed to investigate the risk factors for major chronic diseases. The sample consists of women who were aged 25 to 42 in 1989, identified through state nursing boards in 14 populous states in the United States of America, with a final cohort of over 100 thousand women. The focus of NHS II is to investigate the effects of oral contraceptives, diet, and lifestyle risk factors, particularly in younger women who started using oral contraceptives during adolescence. NHS participants have been followed up every odd year through questionnaires and other modes of data collection, including biological samples.
Study design
Cohort - occupational
Number of participants at first data collection
116,430 (participants)
Age at first data collection
25 - 42 years (participants)
Participant year of birth
Varied (participants)
Participant sex
Female
Representative sample at baseline?
No
Sample features
Country
Year of first data collection
1989
Primary Institutions
Harvard University
Links
Profile paper DOI
Not available
Funders
National Institutes of Health (NIH)
Ongoing?
Yes
Data types collected
- Interview – face-to-face
- Physical or biological assessment (e.g. blood, saliva, gait, grip strength, anthropometry)
- Self-report questionnaire – paper or computer assisted
- None
- None
- None
Engagement
Keywords
Consortia and dataset groups
