Osteoarthritis Initiative (OAI)
The overall aim of the OAI is to improve public health through the prevention or alleviation of pain and disability from osteoarthritis (OA). Participants were over 4,700 adults aged 45 to 79 years recruited at study sites across the United States of America, including the University of Maryland, Johns Hopkins University, the Ohio State University, University of Pittsburgh, and Memorial Hospital of Rhode Island/Brown University. Participants included subs cohorts with symptomatic knee OA at baseline, without OA but at risk for it, and with no OA or known risk factors. Baseline assessment began in 2004 and participants have been followed up every 1 to 2 years for at least 10 years.
Study design
Cohort, Cohort - clinical
Number of participants at first data collection
4,796 (participants)
Age at first data collection
45 - 79 years (participants)
Participant year of birth
Varied (participants)
Participant sex
All
Representative sample at baseline?
No
Sample features
Country
Year of first data collection
2004
Primary Institutions
National Institutes of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
National Institutes of Health (NIH)
Profile paper DOI
Funders
Foundation for the National Institutes of Health (FNIH)
GlaxoSmithKline (GSK)
Merck & Co., Inc.
National Center for Complementary and Alternative Medicine
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Ongoing?
Yes
Data types collected
- Interview – face-to-face
- Interview – phone
- Physical or biological assessment (e.g. blood, saliva, gait, grip strength, anthropometry)
- Self-report questionnaire – paper or computer assisted
- None
- None
- None
Engagement
Keywords
