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Open Access Series of Imaging Studies (OASIS-2)
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OASIS is a project aimed at making neuroimaging data sets of the brain freely available to the scientific community. OASIS currently contains 4 datasets (OASIS-1, OASIS-2, OASIS-3, and OASIS-4). OASIS-2 is the "Longitudinal MRI Data in Nondemented and Demented Older Adults" dataset and includes 150 participants aged 60 to 96 years, many of whom were diagnosed with Alzheimer's disease at some point during their participation. Participants were obtained from the longitudinal pool of the Washington University Alzheimer Disease Research Center (ADRC). Each participant was scanned on two or more visits, separated by at least one year, for a total of 373 imaging sessions.

Study design
Cohort

Number of participants at first data collection

150 (participants)

Age at first data collection

60 - 96 years (participants)

Participant year of birth

Varied (participants)

Participant sex
All

Representative sample at baseline?
No

Sample features

Older and elderly people
Dataset details

Country

United States of America

Year of first data collection

1990

Primary Institutions

Washington University in St. Louis (WashU)

Links

sites.wustl.edu/oasisbrains/home/oasis-2/

nitrc.org/projects/oasis

Funders

Alzheimer‘s Association

Howard Hughes Medical Institute (HHMI)

James S. McDonnell Foundation

Mental Illness and Neuroscience Discovery (MIND) Institute

National Institutes of Health (NIH)

Ongoing?
Yes

Data types collected

neuroImagingData
mentalHealthData
Quantitative data collection
  • Self-report questionnaire – unspecified
Qualitative data collection
  • None
Neuroimaging data collection
  • Magnetic Resonance Imaging (MRI)
Linked or secondary data
  • None
Features

Engagement

  • None
  • Keywords

    Alzheimer's disease (AD)
    Biomarkers
    Brain structure and anatomy
    Clinical assessments
    Dementia
    Mild cognitive impairment (MCI)
    Morphometry
    Neurodegeneration

    Consortia and dataset groups

    ADataViewer
    Global Alzheimer’s Association Interactive Network (GAAIN)
    Open Access Series of Imaging Studies (OASIS)
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