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Open Access Series of Imaging Studies (OASIS-3)
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Sample details

OASIS-3 is a retrospective compilation of data for 1,378 participants that were collected across several ongoing projects in the United States, conducted through Washington University in St. Louis (WUSTL) Knight Alzheimer Disease Research Center (Knight ADRC) over the course of 30 years. Participants include 755 cognitively normal adults and 622 individuals at various stages of cognitive decline, ranging in age from 42 to 95 years.

Study design
Cohort

Number of participants at first data collection

1,378 (participants)

Age at first data collection

42 - 95 years (participants)

Participant year of birth

Varied (participants)

Participant sex
All

Representative sample at baseline?
No

Sample features

Adults
Dataset details

Country

United States of America

Year of first data collection

No information available

Primary Institutions

Washington University in St. Louis (WashU)

Links

sites.wustl.edu/oasisbrains/home/oasis-3/

nitrc.org/projects/oasis3

Funders

National Institutes of Health (NIH)

Ongoing?
Yes

Data types collected

neuroImagingData
Quantitative data collection
  • Computer, paper or task testing (e.g. cognitive testing, theory of mind doll task, attention computer tasks)
  • Interview – face-to-face
  • Physical or biological assessment (e.g. blood, saliva, gait, grip strength, anthropometry)
Qualitative data collection
  • None
Neuroimaging data collection
  • Computerized tomography (CT)
  • Diffusion Tensor Imaging (DTI)
  • Magnetic Resonance Imaging (MRI)
  • Positron Emission Tomography (PET)
Linked or secondary data
  • None
Features

Engagement

  • None
  • Keywords

    Ageing
    Alzheimer's disease (AD)
    Biomarkers
    Brain structure and anatomy
    Cognitive ageing and decline
    Dementia
    Mild cognitive impairment (MCI)
    Neurodegeneration
    Neuroimaging

    Consortia and dataset groups

    ADataViewer
    Global Alzheimer’s Association Interactive Network (GAAIN)
    Open Access Series of Imaging Studies (OASIS)
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