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Personal Assessment and Crisis Evaluation Clinic ultra-high risk cohort recruited in 2000 (PACE Clinic UHR cohort 2000)
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Sample details

This study was a component of a large program of research aiming to address the issues of identifying young people at high risk of psychosis, characterising the transition from high risk to acute psychosis and developing appropriate preventive interventions for this population. Participants were almost 40 young people at a ultra-high risk of developing a psychotic disorder, attending the Personal Assessment and Crisis Evaluation (PACE) Clinic in Melbourne, Australia. Participants were evaluated at baseline in 2000 and were assessed monthly for 12 months and again at 24 months to determine the onset of acute psychosis. Participants have been followed up for psychosis incidence through the PACE 400 and UHR 1000+ cohort studies.

Study design
Cohort, Cohort - clinical

Number of participants at first data collection

39 (participants)

Age at first data collection

14 - 30 years (participants)

Participant year of birth

Varied (participants)

Participant sex
All

Representative sample at baseline?
No

Sample features

Adolescents
High-risk populations
Patients and clinical populations
People with psychiatric conditions
Young adults
Dataset details

Country

Australia

Year of first data collection

2000

Primary Institutions

Orygen Research Centre

Personal Assessment And Crisis Evaluation Clinic (PACE Clinic)

Links

pre-empt.org.au/our-research/uhr-1000/

doi.org/10.1016/j.bpsc.2023.11.009

doi.org/10.1002/wps.21240

Funders

Department of Human Services and Health

National Alliance for Research on Schizophrenia & Depression (NARSAD) (now known as Brain & Behaviour Research Foundation; BBRF)

National Health and Medical Research Council (NHMRC)

Ongoing?
No

Data types collected

neuroImagingData
mentalHealthData
dataLinkage
Quantitative data collection
  • Interview – face-to-face
  • Physical or biological assessment (e.g. blood, saliva, gait, grip strength, anthropometry)
  • Secondary data
Qualitative data collection
  • None
Neuroimaging data collection
  • Magnetic Resonance Imaging (MRI)
Linked or secondary data
  • Healthcare data
Features

Engagement

  • None
  • Keywords

    Adolescence
    Clinically high risk
    Disease onset
    Prodromal symptoms
    Psychiatric diagnoses
    Psychiatry
    Psychosis and psychotic disorders
    Risk factors

    Consortia and dataset groups

    UHR 1000+ cohort
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