Personalized Environment and Genes Study (PEGS)
PEGS follows approximately 20,000 adults to discover how the environment and genes affect health. In 2002, PEGS was initially established as the Environmental Polymorphisms Registry (EPR), and the Environmental Polymorphisms Pilot Study (EPPS) was established to assess willingness to participate in a longitudinal cohort. Based on the favorable response rate, enrolment for PEGS began in 2005 by recruiting individuals living in the greater Research Triangle Park region in North Carolina, United States of America, who reflect the overall demographics of the area in terms of age, gender, race and ethnicity. Participants are primarily female (62%) and white (63%), with a mean age of 50 years. All participants are followed up periodically for up to 25 years after enrolment, and approximately 11,000 are actively engaged with annual contact.
Study design
Cohort - open, Cohort - research programme, Cohort
Number of participants at first data collection
19,445 (participants)
Recruitment is ongoing
Age at first data collection
≥ 18 years (participants)
Participant year of birth
Varied (participants)
Participant sex
All
Representative sample at baseline?
Individuals living in the greater Research Triangle Park region in North Carolina in terms of age, gender, race and ethnicity.
Sample features
Country
Year of first data collection
2002 (EPR/EPPS)
2005 (PEGS)
Primary Institutions
National Institute of Environmental Health Sciences (NIEHS)
Profile paper DOI
Funders
National Institute of Environmental Health Sciences (NIEHS)
Ongoing?
Yes
Data types collected
- Physical environment assessment (e.g. pollution, mould)
- Physical or biological assessment (e.g. blood, saliva, gait, grip strength, anthropometry)
- Secondary data
- Self-completed questionnaire – unspecified
- None
- None
- Geographic, spatial & environmental data
- Healthcare data
Engagement
Keywords
