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Progression and Early detection of Subclinical Atherosclerosis study (PESA)
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Sample details

PESA is a prospective cohort study investigating the prevalence, progression, and determinants of subclinical atherosclerosis. The study included over 4,100 asymptomatic employees aged between 40 and 54 years at baseline working at the Banco Santander Headquarters in Madrid, Spain. All eligible employees were invited to participate at the time of their regular annual check-up performed by the company's medical services. The study also runs a biobank, including blood and urine samples collected from participants.

Study design
Biobank, Cohort - occupational

Number of participants at first data collection

4,184 (participants)

Age at first data collection

40 - 54 years (participants)

Participant year of birth

Varied (participants)

Participant sex
All

Representative sample at baseline?
No

Sample features

Middle-aged people
Occupational
Dataset details

Country

Spain

Year of first data collection

2013

Primary Institutions

National Centre for Cardiovascular Research (Centro Nacional de Investigaciones Cardiovasculares, CNIC)

Links

clinicaltrials.gov/ct2/show/NCT01410318

doi.org/10.1016/j.jacc.2020.12.027

Funders

Botin Foundation (Fundación Botín)

National Centre for Cardiovascular Research (Centro Nacional de Investigaciones Cardiovasculares, CNIC)

Ongoing?
Yes

Data types collected

neuroImagingData
mentalHealthData
dataLinkage
Quantitative data collection
  • Activity log (e.g. food, sleep, exercise)
  • Interview – face-to-face
  • Physical or biological assessment (e.g. blood, saliva, gait, grip strength, anthropometry)
  • Secondary data
Qualitative data collection
  • None
Neuroimaging data collection
  • Magnetic Resonance Imaging (MRI)
  • Positron Emission Tomography (PET)
Linked or secondary data
  • Healthcare data
  • Mortality data
Features

Engagement

  • None
  • Keywords

    Biological samples/biospecimens
    Disease detection
    Disease progression
    Heart disease and conditions
    Occupational
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