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Peri/Postnatal Epigenetics Twin Study (PETS)
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Sample details

PETS follows a cohort of over 200 twin pairs and their mothers from Melbourne, Australia. The included twin pairs consisted of 42.1% monozygotic twins, and 57.9% dizygotic twins. Mothers who were attending multiple pregnancy clinics at three Melbourne hospitals were recruited into the study at 18 to 22 weeks gestation from 2008 to 2011, with data first collected from the twins at birth.

Study design
Cohort - primary caregiver and child, Cohort - twin, Cohort - birth

Number of participants at first data collection

250 (twin pairs)

250 (mothers)

Recruitment is ongoing

Age at first data collection

Birth (twin pairs)

Varied (mothers)

Participant year of birth

2007 - 2009 (twin pairs)

Varied (mothers)

Participant sex
All

Representative sample at baseline?
No

Sample features

Dizygotic and monozygotic twins
Mothers
Dataset details

Country

Australia

Year of first data collection

2007

Primary Institutions

Murdoch Children’s Research Institute (MCRI)

Links

mcri.edu.au/research/projects/peripostnatal-epigenetic-twins-study-pets

lifecourse.melbournechildrens.com/cohorts/pets/

Profile paper DOI

doi.org/10.1093/ije/dyr140

Funders

Academy of Finland

Bonnie Babes Foundation

Financial Markets Foundation for Children (FMFC)

Finnish Cultural Foundation (Suomen Kulttuurirahasto)

National Health and Medical Research Council (NHMRC)

Ongoing?
Yes

Data types collected

neuroImagingData
mentalHealthData
Quantitative data collection
  • Computer, paper or task testing (e.g. cognitive testing, theory of mind doll task, attention computer tasks)
  • Physical or biological assessment (e.g. blood, saliva, gait, grip strength, anthropometry)
  • Self-report questionnaire – unspecified
Qualitative data collection
  • None
Neuroimaging data collection
  • Magnetic Resonance Imaging (MRI)
Linked or secondary data
  • None
Features

Engagement

  • Community engagement
  • Keywords

    Biological samples/biospecimens
    Chronic illness
    Disease risk
    Epigenetics
    Gene-environment interactions (GxE)
    Infant biosamples
    Motherhood
    Postnatal factors
    Prenatal exposures

    Consortia and dataset groups

    COllaborative project of Development of Anthropometrical measures in Twins (CODATwins) project
    Methylation, Imaging and NeuroDevelopment (MIND) Consortium
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