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Perinatal Imaging Partnership with Families (PIPKIN)
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Sample details

PIPKIN is a unique cohort study investigating the early development of foetal and infant neurocognitive function and behaviour, and how the infants social and family environment shapes this development. Beginning in June 2022, a total of 125 participants were recruited from Cambridge (United Kingdom) and surrounding villages via either a maternity hospital or social media and community flyer advertisements. After recruitment, the study involves two antenatal visits at 32 and 24 weeks' gestation, two home visits in the first 2 to 3 weeks after birth, and additional visits at 1 month and 5 months, with a final interview/questionnaire occurring 9 months post-birth. Data collection, for all participants' follow-ups, is due to conclude in March 2026.

Study design
Cohort - primary caregiver and child, Cohort

Number of participants at first data collection

125 (families, as of 2025)

Age at first data collection

Varied (families)

Participant year of birth

Varied (families)

Participant sex
All

Representative sample at baseline?
No

Sample features

Community-based sample
Pregnant people
Singletons
Dataset details

Country

United Kingdom of Great Britain and Northern Ireland

Year of first data collection

2022

Primary Institutions

University of Cambridge (Academic, United Kingdom)

Links

pipkinstudy.com/

hra.nhs.uk/planning-and-improving-research/application-summaries/research-summaries/pipkin-study/

Funders

Biomedical Research Centre (BRC) (Academic, United Kingdom)

Medical Research Council (MRC) (Research council, United Kingdom)

National Institute for Health and Care Research (NIHR) (Government, United Kingdom)

Ongoing?
Yes

Data types collected

neuroImagingData
mentalHealthData
Quantitative data collection
  • Activity log (e.g. food, sleep, exercise)
  • Audio or visual recordings (e.g. of child behaviour, facial expressions)
  • Computer, paper or task testing (e.g. cognitive testing, theory of mind doll task, attention computer tasks)
  • Interview – phone
  • Physical or biological assessment (e.g. blood, saliva, gait, grip strength, anthropometry)
  • Self-completed questionnaire – online
Qualitative data collection
  • None
Neuroimaging data collection
  • Electroencephalography (EEG)
  • Near-infrared spectroscopy (NIRS)
Linked or secondary data
  • None
Features

Engagement

  • Community engagement
  • Keywords

    Biological samples/biospecimens
    Brain development
    Family environment and factors
    Infant biosamples
    Infant exposures
    Neurocognitive development
    Neuroimaging
    Paediatric development
    Parenting and family
    Perinatal exposures
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