Perinatal Adverse events and Special Trends in Cognitive Trajectory (PLASTICITY)
PLASTICITY is a prospective longitudinal study of brain development and the effects of adverse pre- and perinatal conditions. The study follows a cohort of 1,196 newborns with one or several pre-defined perinatal risks, such as low birth weight. The newborns were recruited from 22,359 consecutive deliveries between 1971 and 1974 at Kätilöopisto hospital in Helsinki, Finland. A control group of 169 children with no perinatal risks born in the same hospital was also followed from childhood. The risk cohort and their controls have been followed up at 5, 9, 16 and 30 years of age, with waves of data collection planned for ages 40, 50 and 60. Over time, surveys have included self-reports and parents’ and teachers’ questionnaires.
Study design
Cohort - birth
Number of participants at first data collection
1,196 (birth risk cohort)
169 (healthy control cohort)
Age at first data collection
5 - 9 years (healthy control cohort)
Birth (birth risk cohort)
Participant year of birth
1971 - 1974 (healthy control cohort)
1971 - 1974 (birth risk cohort)
Participant sex
All
Representative sample at baseline?
No
Sample features
Country
Year of first data collection
1971 - 1974 (birth risk cohort)
1976 - 1979 (healthy control cohort)
Primary Institutions
University of Helsinki (Helsingin yliopisto)
Profile paper DOI
Funders
Academy of Finland
Association for Life Insurance Companies
Foundation of Pediatric Research (Lastentautien Tutkimussäätiö)
Rinnekodit Foundation
Signe and Ane Gyllenberg Foundation
Ongoing?
Yes
Data types collected
- Computer, paper or task testing (e.g. cognitive testing, theory of mind doll task, attention computer tasks)
- Interview – face-to-face
- Physical or biological assessment (e.g. blood, saliva, gait, grip strength, anthropometry)
- Secondary data
- Self-report questionnaire – paper or computer assisted
- None
- Diffusion Tensor Imaging (DTI)
- Electroencephalography (EEG)
- Functional magnetic resonance imaging (fMRI)
- Magnetic Resonance Imaging (MRI)
- Magnetoencephalography (MEG)
- Healthcare data
- Social care data
- Tax, income & benefit data
Engagement
Keywords
