Prechter Longitudinal Study of Bipolar Disorder (PLS-BD)
The PLS-BD is an open cohort study that began in 2005 in the United States on adults with a diagnosis of bipolar disorder and without a history of schizophrenia. The primary clinical source of participants was from admissions to the University of Michigan (UM) Health System psychiatric outpatient and inpatient clinical services. Participants complete self-report questionnaires every two months and annual follow-up visits for ten years and beyond. Of the 1,111 participants who were enrolled, 960 (86%) had longitudinal data defined as two or more observations at different time points over the follow-up period. At enrolment, the average age of participants was 38.64 years, and 66% identified as female.
Study design
Cohort - clinical, Cohort - open
Number of participants at first data collection
1,111 (participants)
Recruitment is ongoing
Age at first data collection
≥ 18 years (participants)
Participant year of birth
Varied (participants)
Participant sex
All
Representative sample at baseline?
No
Sample features
Country
Year of first data collection
2005
Primary Institutions
University of Michigan
Profile paper DOI
Funders
Heinz C Prechter Bipolar Research Fund
Kelly Elizabeth Beld Memorial Fund
National Institutes of Health (NIH)
Richard Tam Foundation
Steven Schwartzberg Memorial Fund
Ongoing?
Yes
Data types collected
- Interview – face-to-face
- Interview – online
- Interview – phone
- Physical or biological assessment (e.g. blood, saliva, gait, grip strength, anthropometry)
- Self-report questionnaire – online
- None
- None
- None
Engagement
Keywords
