Population-level detection of early loss of kidney function: 7-year follow-up of a young adult cohort at risk of Mesoamerican nephropathy
This study follows two community-based cohorts of healthy adults aged between 18 and 30 years across 11 rural communities in León and Chinandega departments in northwest Nicaragua. Cohort 1 consisted of over 350 participants, with seven years of follow up conducted. Cohort 2 consisted of over 400 participants, with three years of follow up conducted. Eligible participants without self-reported diabetes, hypertension, or a chronic kidney disease diagnosis, were invited to participate following population census administration in the participating communities.
Study design
Cohort
Number of participants at first data collection
351 (cohort 1 participants)
420 (cohort 2 participants)
Age at first data collection
18 - 30 years (participants)
Participant year of birth
Varied (participants)
Participant sex
All
Representative sample at baseline?
No
Sample features
Country
Year of first data collection
2014
Primary Institutions
University College London (UCL) (Academic, United Kingdom)
Links
No website available
Profile paper DOI
Funders
Dutch National Postcode Lottery (Nationale Postcode Loterij) (Third Sector, Netherlands)
Medical Research Council (MRC) (Research council, United Kingdom)
The Colt Foundation (Third Sector, United Kingdom)
Ongoing?
Yes
Data types collected
- Interview – face-to-face
- Physical or biological assessment (e.g. blood, saliva, gait, grip strength, anthropometry)
- None
- None
- None
Engagement
Keywords
