Prediction and Prevention of Preeclampsia and Intrauterine Growth Restriction Study (PREDO)
The PREDO study is a prospective, multicentre study of Finnish women who were pregnant between 2005 and 2009 and their children. The PREDO study cohort was set up to identify novel risk factors and biomarkers in pregnant women associated with the development of preeclampsia and intrauterine growth restriction (IUGR). PREDO recruited women with a singleton, intrauterine pregnancy who visited antenatal clinics at any of the 10 study hospitals for their first ultrasound screening. The antenatal clinics were spread across Southern and Eastern Finland. Partners (biological fathers) of the pregnant women were also invited to participate via an invitation letter given to the pregnant women. Partners who volunteered to participate provided a blood sample and completed a study questionnaire.
Study design
Cohort - primary caregiver and child
Number of participants at first data collection
4,777 (mother and child dyads)
575 (fathers)
Age at first data collection
Birth (children)
17 - 47 years (mothers)
Varied (fathers)
Participant year of birth
2006 - 2010 (children)
Varied (mothers)
Varied (fathers)
Participant sex
Female
Representative sample at baseline?
Key birth outcomes (gestational age at birth and birthweight) to that of the broader Finnish population.
Sample features
Country
Year of first data collection
2006
Primary Institutions
Helsinki and Uusimaa Hospital District (Helsingin ja Uudenmaan sairaanhoitopiiri, HUS)
University of Helsinki (Helsingin yliopisto)
Links
No website available
Profile paper DOI
Funders
Academy of Finland
Emil Aaltonen Foundation (Emil Aaltosen Säätiö)
EraNet
Finnish Medical Foundation (Suomen Lääketieteen Säätiölle)
Jane and Aatos Erkko Foundation
Ongoing?
Yes
Data types collected
- Interview – face-to-face
- Physical or biological assessment (e.g. blood, saliva, gait, grip strength, anthropometry)
- Secondary data
- Self-report questionnaire – unspecified
- None
- None
- Healthcare data
- Medical birth registry
Engagement
Keywords
