Pre-symptomatic Evaluation of Experimental or Novel Treatments for AD (PREVENT-AD)
PREVENT-AD was designed to investigate the pathogenesis of Alzheimer's disease (AD). The study recruited cognitively normal adults aged 60 years and older who had a first-degree relative with AD-like dementia. Individuals between 55 and 59 years old were also included if they were less than 15 years younger than a first-degree relative who had already developed AD. This resulted in a baseline cohort of 425 adults, mostly from the greater Montreal region of Quebec, Canada.
Study design
Cohort
Number of participants at first data collection
425 (participants)
Age at first data collection
≥ 55 years (participants)
Participant year of birth
Varied (participants)
Participant sex
All
Representative sample at baseline?
No
Sample features
Country
Year of first data collection
2011
Primary Institutions
Johns Hopkins University (JHU)
McGill University
University of Montreal (Université de Montréal, UdeM)
Profile paper DOI
Funders
Canadian Foundation for Innovation (Fondation canadienne pour l’innovation, FCI)
Douglas Hospital Research Centre and Foundation
Fondation J-Louis Lévesque
Fonds de Recherche du Québec – Santé (FRQ-S)
Government of Canada
Ongoing?
Yes
Data types collected
- Computer, paper or task testing (e.g. cognitive testing, theory of mind doll task, attention computer tasks)
- Interview – online
- Physical or biological assessment (e.g. blood, saliva, gait, grip strength, anthropometry)
- None
- Functional magnetic resonance imaging (fMRI)
- Magnetic Resonance Imaging (MRI)
- None
Engagement
Keywords
Consortia and dataset groups
