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PSYSCAN
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Sample details

PSYSCAN is an international, multicenter study examining the early stages of psychosis. Between 2016 and 2019, the study recruited participants, aged between 14 and 40 years, from across Europe, North America, South America, Asia, and Australia. The study comprised three cohorts: 239 individuals at clinical high risk of psychosis (CHR-P), 328 patients who experienced a first episode of psychosis (FEP), and 139 healthy controls (HC). All participants were assessed at baseline. FEP participants were followed up at 2, 6, and 12 months. CHR-P participants were followed up at 3, 6, 12, 18, and 24 months. HC participants were followed up at 6 and 12 months.

Study design
Cohort - clinical

Number of participants at first data collection

328 (FEP participants)

239 (CHR-P participants)

139 (HC participants)

Age at first data collection

Varied (FEP participants)

Varied (CHR-P participants)

Varied (HC participants)

Participant year of birth

Varied (FEP participants)

Varied (CHR-P participants)

Varied (HC participants)

Participant sex
All

Representative sample at baseline?
No

Sample features

Adolescents
Adults
Control participants
Patients and clinical populations
Psychosis
Dataset details
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Countries

Australia, Austria, Brazil, Canada, China

Year of first data collection

2016

Primary Institutions

Federal University of São Paulo (Universidade Federal de São Paulo, UNIFESP)

Centro de Investigación Biomédica en Red del área de Salud Mental (CIBERSAM)

King's College London (KCL)

Maastricht University Medical Center (Maastricht UMC+)

Queen Mary Hospital

Links

doi.org/10.1016/j.schres.2024.02.018

Funders

European Commission Seventh Framework Programme

Ongoing?
No

Data types collected

neuroImagingData
mentalHealthData
dataLinkage
Quantitative data collection
  • Computer, paper or task testing (e.g. cognitive testing, theory of mind doll task, attention computer tasks)
  • Interview – face-to-face
  • Interview – online
  • Interview – phone
  • Physical or biological assessment (e.g. blood, saliva, gait, grip strength, anthropometry)
  • Secondary data
Qualitative data collection
  • None
Neuroimaging data collection
  • Diffusion Tensor Imaging (DTI)
  • Functional magnetic resonance imaging (fMRI)
  • Magnetic Resonance Imaging (MRI)
Linked or secondary data
  • Healthcare data
Features

Engagement

  • Community engagement
  • Keywords

    Biological samples/biospecimens
    Cognition
    Functional status
    Genetics
    Medical history
    Medication
    Neuroimaging
    Psychiatry
    Psychosis and psychotic disorders
    Schizophrenia
    Sociodemographics
    Substance use
    Treatment strategies

    Consortia and dataset groups

    Harmonization of At Risk Multisite Observational Networks for Youth (HARMONY) collaboration
    UHR 1000+ cohort
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