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Rancho Bernardo Study (RBS)
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Sample details

The RBS study is a long-running longitudinal cohort study based in Rancho Bernardo, a suburb of San Diego, California, the United States of America. Over 6,700 participants were initially recruited between 1972 and 1974 to investigate cardiovascular risk factors. The study was later expanded to examine broader aspects of aging. Participants were recruited through door-to-door outreach and community engagement as part of the Lipid Research Clinic (LRC) Prevalence Program, with free health screenings conducted in a mobile clinic set up in a supermarket parking lot. To date, the study has conducted 12 clinic visits, with participants followed up through clinic visits approximately every 4 years, mailed surveys every 2 years, and annual checks on vital status.

Study design
Cohort

Number of participants at first data collection

6,726 (participants)

Age at first data collection

30 - 79 years (participants)

Participant year of birth

Varied (participants)

Participant sex
All

Representative sample at baseline?
No

Sample features

Adults
Community-based sample
Older and elderly people
Dataset details

Country

United States of America

Year of first data collection

1972

Primary Institutions

University of California, San Diego (UC San Diego)

Links

knit.ucsd.edu/ranchobernardostudy

knit.ucsd.edu/ranchobernardostudy/wp-content/uploads/sites/23/2020/02/McEvoy_GSA-2019-Final.pdf

doi.org/10.1016/j.archger.2025.105870

Funders

Agency for Healthcare Research and Quality (AHRQ)

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

National Institute on Aging (NIA)

National Institute on Alcohol Abuse and Alcoholism (NIAAA)

Ongoing?
Yes

Data types collected

neuroImagingData
mentalHealthData
dataLinkage
Quantitative data collection
  • Computer, paper or task testing (e.g. cognitive testing, theory of mind doll task, attention computer tasks)
  • Physical or biological assessment (e.g. blood, saliva, gait, grip strength, anthropometry)
  • Secondary data
  • Self-report questionnaire – paper or computer assisted
Qualitative data collection
  • None
Neuroimaging data collection
  • Magnetic Resonance Imaging (MRI)
Linked or secondary data
  • Mortality data
Features

Engagement

  • Patients, service users, lived experience involvement
  • Community engagement
  • Keywords

    Ageing
    Biomarkers
    Bone density
    Cardiovascular health and disease
    Cognitive function
    Diabetes
    Genetics
    Life outcomes
    Lifecourse
    Osteoporosis
    Psychosocial factors
    Sex-specific differences
    Sub-studies
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