Respiratory Health in Northern Europe (RHINE )
RHINE is a population-based cohort study longitudinally examining respiratory symptoms, diseases and environmental exposures in participants from seven Northern European centres (Reykjavik in Iceland, Bergen in Norway, Umeå, Uppsala and Gothenburg in Sweden, Aarhus in Denmark and Tartu in Estonia). The cohort included nearly 22,000 adults born between 1945 and 1973 who had participated in Stage 1 of the European Community Respiratory Health Survey (ECRHS) at the seven Nordic study centres between 1990 and 1994. The participants have been followed up in 1999-2001 (RHINE II), 2010-2012 (RHINE III), and 2022-2023 (RHINE IV). Since 2012, the offspring and parents of RHINE participants are being followed up as part of the RHINESSA study.
Study design
Cohort
Number of participants at first data collection
21,802 (participants)
Age at first data collection
20 - 44 years (participants)
Participant year of birth
1945 - 1973 (participants)
Participant sex
All
Representative sample at baseline?
No
Sample features
Countries
Year of first data collection
1990
Primary Institutions
Aarhus University (Aarhus Universitet, AU)
Umeå University (Umeå Universitet)
University of Bergen (Universitetet i Bergen, UiB)
University of Gothenburg (Göteborgs universitet)
University of Iceland
Profile paper DOI
Funders
Bror Hjerpstedt Foundation
Danish Lung Association (Danmarks Lungeforening)
Estonian Research Council
Norwegian Asthma and Allergy Association (Norges Astma- og Allergiforbund, NAAF)
Norwegian Research Council (Norges forskningsråd)
Ongoing?
No
Data types collected
- Secondary data
- Self-completed questionnaire – paper or computer assisted
- None
- None
- Census data
- Existing research data
- Geographic, spatial & environmental data
- Healthcare data
- Mortality data
Engagement
Keywords
Consortia and dataset groups
