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Respiratory Health in Northern Europe (RHINE )
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Sample details

RHINE is a population-based cohort study longitudinally examining respiratory symptoms, diseases and environmental exposures in participants from seven Northern European centres (Reykjavik in Iceland, Bergen in Norway, Umeå, Uppsala and Gothenburg in Sweden, Aarhus in Denmark and Tartu in Estonia). The cohort included nearly 22,000 adults born between 1945 and 1973 who had participated in Stage 1 of the European Community Respiratory Health Survey (ECRHS) at the seven Nordic study centres between 1990 and 1994. The participants have been followed up in 1999-2001 (RHINE II), 2010-2012 (RHINE III), and 2022-2023 (RHINE IV). Since 2012, the offspring and parents of RHINE participants are being followed up as part of the RHINESSA study.

Study design
Cohort

Number of participants at first data collection

21,802 (participants)

Age at first data collection

20 - 44 years (participants)

Participant year of birth

1945 - 1973 (participants)

Participant sex
All

Representative sample at baseline?
No

Sample features

Adults
Survey participants
Dataset details
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Countries

Denmark, Estonia, Iceland, Norway, Sweden

Year of first data collection

1990

Primary Institutions

Aarhus University (Aarhus Universitet, AU) (Academic, Denmark)

Umeå University (Umeå Universitet) (Academic, Sweden)

University of Bergen (Universitetet i Bergen, UiB) (Academic, Norway)

University of Gothenburg (Göteborgs universitet) (Academic, Sweden)

University of Iceland (Academic, Iceland)

Links

rhine.w.uib.no/

maelstrom-research.org/study/rhine

breathesweden.com/rhine/

researchdata.se/en/catalogue/dataset/ext0164-1

Funders

Bror Hjerpstedt Foundation (Third Sector, Sweden)

Danish Lung Association (Danmarks Lungeforening) (Third Sector, Denmark)

Estonian Research Council (Research council, Estonia)

Icelandic Centre for Research (Rannsóknamiðstöð Íslands, RANNÍS) (Government, Iceland)

Norwegian Asthma and Allergy Association (Norges Astma- og Allergiforbund, NAAF) (Third Sector, Norway)

Ongoing?
No

Data types collected

mentalHealthData
dataLinkage
Quantitative data collection
  • Secondary data
  • Self-completed questionnaire – paper or computer assisted
Qualitative data collection
  • None
Neuroimaging data collection
  • None
Linked or secondary data
  • Census data
  • Existing research data
  • Geographic, spatial & environmental data
  • Healthcare data
  • Mortality data
Features

Engagement

  • None
  • Keywords

    Allergies
    Asthma
    Chronic obstructive pulmonary disease (COPD)
    Environmental exposures
    Lifestyle factors
    Occupational exposure
    Pollution
    Respiratory health and disease
    Risk factors
    Sleep

    Consortia and dataset groups

    Swedish Cohort Consortium (Cohorts.se)
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