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Religious Orders Study (ROS)
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Sample details

ROS investigates memory and movement problems associated with ageing. The study recruits nuns, priests, and monks (brothers) of religious orders living communally, whether employed or retired, across the United States of America. Participants are from states including California, Illinois, Indiana, Iowa, Kentucky, Louisiana, Maryland, Minnesota, New York, Pennsylvania, Tennessee, Texas, Washington DC and Wisconsin. 354 participants were included in the baseline data collection in 1994. All participants have agreed to donate their brains for further research after death allowing for post-mortem studies. As of 2024, the study has over 1,500 active participants while autopsies have been conducted on 919 former participants.

Study design
Cohort

Number of participants at first data collection

1,503 (participants as of 2024)

Recruitment is ongoing

Age at first data collection

≥ 65 years (participants)

Participant year of birth

Varied (participants)

Participant sex
All

Representative sample at baseline?
No

Sample features

Clergy
Ethnically diverse populations
Monks
Nuns
Racial and ethnic minorities
Dataset details

Country

United States of America

Year of first data collection

1994

Primary Institutions

Rush University

Links

rushu.rush.edu/research/departmental-research/rush-alzheimers-disease-center/rush-alzheimers-disease-center-research/epidemologic-research/religious-orders-study

ncbi.nlm.nih.gov/pmc/articles/pmc3409291/

Profile paper DOI

doi.org/10.3233/jad-179939

Funders

National Institute on Aging (NIA)

Ongoing?
Yes

Data types collected

neuroImagingData
mentalHealthData
dataLinkage
Quantitative data collection
  • Computer, paper or task testing (e.g. cognitive testing, theory of mind doll task, attention computer tasks)
  • Physical or biological assessment (e.g. blood, saliva, gait, grip strength, anthropometry)
  • Secondary data
  • Self-report questionnaire – unspecified
  • Wearable devices
Qualitative data collection
  • None
Neuroimaging data collection
  • Magnetic Resonance Imaging (MRI)
Linked or secondary data
  • Census data
Features

Engagement

  • None
  • Keywords

    Ageing
    Alzheimer's disease (AD)
    Autopsy
    Biological samples/biospecimens
    Cognitive ageing and decline
    Dementia
    Memory loss
    Mild cognitive impairment (MCI)
    Risk factors
    Sub-studies

    Consortia and dataset groups

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