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Radboud University Nijmegen Diffusion Tensor and Magnetic Resonance Cohort Study (RUN DMC)
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Sample details

The RUN DMC study is a prospective cohort study in Nijmegen, Netherlands, among 503 non-demented participants aged between 50 and 85 years at baseline. The baseline assessment was conducted in 2006 and follow-up assessment was in 2012. Patients were referred either because of acute symptoms, such as transient ischemic attack (TIA) or lacunar syndromes, or subacute complaints such as cognitive, motor disturbances, and/or depressive symptoms.

Study design
Cohort - clinical

Number of participants at first data collection

503 (participants)

Age at first data collection

50 - 85 years (participants)

Participant year of birth

Varied (participants)

Participant sex
All

Representative sample at baseline?
No

Sample features

Patients and clinical populations
Dataset details

Country

Netherlands

Year of first data collection

2006

Primary Institutions

Radboud University Medical Center (Radboudumc)

Links

doi.org/10.1001/jamaneurol.2015.4560

Profile paper DOI

doi.org/10.3233/jad-150573

Funders

Dutch Research Council (Nederlandse Organisatie voor Wetenschappelijk Onderzoek, NWO)

University of Twente (Universiteit Twente, UT)

Ongoing?
Yes

Data types collected

neuroImagingData
mentalHealthData
dataLinkage

Quantitative data collection

  • Computer, paper or task testing (e.g. cognitive testing, theory of mind doll task, attention computer tasks)
  • Interview – face-to-face
  • Physical or biological assessment (e.g. blood, saliva, gait, grip strength, anthropometry)
  • Secondary data

Qualitative data collection

  • None

Neuroimaging data collection

  • Diffusion Tensor Imaging (DTI)
  • Magnetic Resonance Imaging (MRI)

Linked or secondary data

  • Healthcare data

Features

Engagement

  • Community engagement
  • Community engagement
  • Keywords

    Biomarkers
    Brain structure and anatomy
    Cognitive impairment and disorders
    Dementia
    Diagnostic markers
    Motor difficulties
    Neurodegeneration
    Neuroimaging
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