Singapore PREconception Study of Long-Term Maternal and Child Outcomes (S-PRESTO)
S-PRESTO investigates pre-pregnancy influences on maternal and child health. 1039 Chinese, Malay or Indian (or any combinations thereof) women aged 18–45 years, intending to conceive and deliver in Singapore were recruited between 2015 and 2017. During pregnancy, six visits were conducted between 6- and 36-weeks’ gestation in the 475 women who successfully conceived. After delivery, offspring were examined at regular intervals from birth until 8 years of age. The mothers were followed up from preconception until 8 years postpartum, and their partners were also seen across multiple timepoints from preconception until postnatal year 2.
Study design
Cohort - primary caregiver and child
Number of participants at first data collection
1,039 (mothers)
373 (children)
298 (partners)
Age at first data collection
Birth (children)
18 - 45 years (mothers)
Participant year of birth
Varied (participants)
Participant sex
Female
Representative sample at baseline?
The S-PRESTO study draws from the three major Asian ethnic groups that represent 50% of the global population.
Sample features
Country
Year of first data collection
2015
Primary Institutions
National University Health System (NUHS)
Singapore Institute for Clinical Sciences (SICS)
Profile paper DOI
Funders
National Medical Research Council (NMRC)
National Research Foundation (NRF)
Singapore Institute for Clinical Sciences (SICS)
Ongoing?
Yes
Data types collected
- Computer, paper or task testing (e.g. cognitive testing, theory of mind doll task, attention computer tasks)
- Interview – face-to-face
- Physical environment assessment (e.g. pollution, mould)
- Physical or biological assessment (e.g. blood, saliva, gait, grip strength, anthropometry)
- Self-report questionnaire – online
- Self-report questionnaire – paper or computer assisted
- None
- Electroencephalography (EEG)
- Magnetic Resonance Imaging (MRI)
- Magnetic Resonance Spectroscopy (MRS)
- Healthcare data
Engagement
Keywords
Consortia and dataset groups
