The SCOT study was designed to investigate the link between the genus beta human papillomavirus (HPV) and squamous cell skin cancer (SCSC). The study involved two cohorts in Seattle, Washington (United States of America). The retrospective cohort included 2,004 kidney and heart transplant recipients who received their transplants between 1995 and 2010. This cohort was first assessed between 2008 and 2011 at recruitment and followed up one and two years after recruitment. Within the retrospective cohort, a case-control study was conducted involving 172 cases with SCSC and 337 matched control subjects. The prospective cohort included 328 individuals on the kidney and heart transplant waiting lists between 2009 and 2011. Data was collected pre-transplant between 2008 and 2011, and one and two years post-transplant.
Study design
Cohort, Cohort - clinical
Number of participants at first data collection
2,004 (retrospective cohort)
328 (prospective cohort)
Age at first data collection
≥ 18 years (retrospective cohort)
≥ 25 years (prospective cohort)
Participant year of birth
Varied (retrospective cohort)
Varied (prospective cohort)
Participant sex
All
Representative sample at baseline?
No
Sample features
Country
Year of first data collection
2008
Primary Institutions
Fred Hutchinson Cancer Center
University of Washington (UW)
Links
No website available
Profile paper DOI
Funders
National Cancer Institute (NCI)
Ongoing?
No
Data types collected
Engagement
Keywords