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Skin Cancer After Organ Transplant Study (SCOT)
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Sample details

The SCOT study was designed to investigate the link between the genus beta human papillomavirus (HPV) and squamous cell skin cancer (SCSC). The study involved two cohorts in Seattle, Washington (United States of America). The retrospective cohort included 2,004 kidney and heart transplant recipients who received their transplants between 1995 and 2010. This cohort was first assessed between 2008 and 2011 at recruitment and followed up one and two years after recruitment. Within the retrospective cohort, a case-control study was conducted involving 172 cases with SCSC and 337 matched control subjects. The prospective cohort included 328 individuals on the kidney and heart transplant waiting lists between 2009 and 2011. Data was collected pre-transplant between 2008 and 2011, and one and two years post-transplant.

Study design
Cohort, Cohort - clinical

Number of participants at first data collection

2,004 (retrospective cohort)

328 (prospective cohort)

Age at first data collection

≥ 18 years (retrospective cohort)

≥ 25 years (prospective cohort)

Participant year of birth

Varied (retrospective cohort)

Varied (prospective cohort)

Participant sex
All

Representative sample at baseline?
No

Sample features

Adults
Cancer patients
Organ transplant patients and donors
Dataset details

Country

United States of America

Year of first data collection

2008

Primary Institutions

Fred Hutchinson Cancer Center

University of Washington (UW)

Links
No website available

Profile paper DOI

doi.org/10.1093/ije/dys179

Funders

National Cancer Institute (NCI)

Ongoing?
No

Data types collected

dataLinkage
Quantitative data collection
  • Interview – face-to-face
  • Physical or biological assessment (e.g. blood, saliva, gait, grip strength, anthropometry)
  • Secondary data
  • Self-report questionnaire – paper or computer assisted
Qualitative data collection
  • None
Neuroimaging data collection
  • None
Linked or secondary data
  • Healthcare data
Features

Engagement

  • None
  • Keywords

    Biological samples/biospecimens
    Cancer
    Comorbidity
    Demographics
    Family health history
    Genotyping
    Medical history
    Medical records
    Medication
    Organ donation and transplants
    Physical health
    Reproductive history
    Skin conditions
    Smoking
    Sun exposure
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