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Seveso Women's Health Study (SWHS)
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Sample details

The SWHS is a historical cohort study investigating the effects of dioxin exposure on the health of women and in utero exposure during a 1976 industrial accident in Seveso, Italy. Baseline assessments were conducted in 1996 on 981 women who were living in Seveso at the time of the explosion. Follow-ups were conducted roughly 20, 30, and 40 years after the accident(1996-98, 2008-09, 2014-16), with the third follow-up also assessing the participants' children who were born after the explosion (Seveso Second Generation).

Study design
Cohort

Number of participants at first data collection

981 (participants)

Age at first data collection

Varied (participants)

Participant year of birth

Varied (participants)

Participant sex
Female

Representative sample at baseline?
No

Sample features

At-risk
Children and young people
Middle-aged people
Newborns, infants and babies
Women
Dataset details

Country

Italy

Year of first data collection

1996

Primary Institutions

University of California, Berkeley (UC Berkeley)

Links

cerch.berkeley.edu/research-programs/seveso-womens-health-study

doi.org/10.1289/ehp.1103720

Funders

Endometriosis Association

Fondazione Lombardia Ambiente

National Institute of Environmental Health Sciences (NIEHS)

National Institutes of Health (NIH)

Regione Lombardia

Ongoing?
No

Data types collected

dataLinkage
Quantitative data collection
  • Interview – face-to-face
  • Physical or biological assessment (e.g. blood, saliva, gait, grip strength, anthropometry)
  • Secondary data
Qualitative data collection
  • None
Neuroimaging data collection
  • None
Linked or secondary data
  • Healthcare data
  • Mortality data
  • Other government data
Features

Engagement

  • None
  • Keywords

    Biological samples/biospecimens
    Cancer
    Chemical exposures
    Child outcomes
    Disasters
    Endocrine disruptors
    Environmental exposures
    Fertility
    Menstruation
    Perinatal exposures
    Perinatal health
    Reproductive health
    Women's health
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