The SWHS is a historical cohort study investigating the effects of dioxin exposure on the health of women and in utero exposure during a 1976 industrial accident in Seveso, Italy. Baseline assessments were conducted in 1996 on 981 women who were living in Seveso at the time of the explosion. Follow-ups were conducted approximately 20, 30, and 40 years after the accident (1996-98, 2008-09, 2014-16), with the third follow-up also assessing the participants' children who were born after the explosion (Seveso Second Generation).
Study design
Cohort
Number of participants at first data collection
981 (participants)
611 (children of participants)
Age at first data collection
Varied (participants)
7 - 17 years (children of participants)
Participant year of birth
Varied (participants)
Varied (children of participants)
Participant sex
Female
Representative sample at baseline?
No
Sample features
Country
Year of first data collection
1996
Primary Institutions
University of California, Berkeley (UC Berkeley) (Academic, United States of America)
Profile paper DOI
Funders
Endometriosis Association (Third Sector, United States of America )
Fondazione Lombardia Ambiente (Third Sector, Italy)
National Institute of Environmental Health Sciences (NIEHS) (Government, United States of America)
National Institutes of Health (NIH) (Government, United States of America)
Regione Lombardia (Government, Italy)
Ongoing?
No
Data types collected


Engagement
Keywords