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Shanghai Cohort Study on Mild Cognitive Impairment
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Sample details

This study aimed to identify individuals with Mild Cognitive Impairment (MCI) who convert to Alzheimer's Disease (AD), and to explore factors associated with the conversion. The study recruited 400 participants between 2012 and 2014, with mild cognitive impairment (MCI), up to 90 years old, whilst residing in Shanghai, China. Participants were followed up every 12 months and completed phone interviews at the 6th and 18th months. The primary endpoint was the time from diagnosis to the conversion from MCI to probable AD. The study ran until March 2017.

Study design
Cohort - clinical, Cohort

Number of participants at first data collection

400 (participants)

Age at first data collection

≤ 90 years (participants)

Participant year of birth

Varied (participants)

Participant sex
All

Representative sample at baseline?
No

Sample features

People with mild and major neurocognitive disorders
Dataset details

Country

China

Year of first data collection

2012

Primary Institutions

Fudan University (复旦大学) (Academic, China)

Links

clinicaltrials.gov/study/NCT01552265

neurodegenerationresearch.eu/cohort/shanghai-cohort-study-on-mild-cognitive-impairment/

benthamscience.com/article/94863

Funders

Foundation of Biomedical Research and Innovation (Healthcare/Medical, Japan)

Translational Research Center for Medical Innovation (Healthcare/Medical, Japan)

Ongoing?
No

Data types collected

neuroImagingData
mentalHealthData
Quantitative data collection
  • Computer, paper or task testing (e.g. cognitive testing, theory of mind doll task, attention computer tasks)
  • Interview – face-to-face
  • Interview – phone
  • Physical or biological assessment (e.g. blood, saliva, gait, grip strength, anthropometry)
Qualitative data collection
  • None
Neuroimaging data collection
  • Magnetic Resonance Imaging (MRI)
Linked or secondary data
  • None
Features

Engagement

  • None
  • Keywords

    Alzheimer's disease (AD)
    Biological samples/biospecimens
    Caregiving
    Dementia
    Disease progression
    Magnetic Resonance Imaging (MRI)
    Mild cognitive impairment (MCI)
    Neurological examination
    Neurology and neurological diseases
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