Strong Heart Study (SHS)
The SHS is a study of cardiovascular disease and its risk factors among Native American (also called American Indian, First American, or Indigenous American) men and women in the United States of America. At baseline, the study initially included over 4,500 participants aged 45-74 years, recruited across 12 Native American tribal nations and communities, including the Gila River Indian Community (GRIC) and Salt River Indian Community(SRIC) in Arizona, the Apache, Caddo, Comanche, Delaware, Fort Sill Apache, Kiowa and Wichita tribal nations in Oklahoma, the Oglala Sioux, and Cheyenne River Sioux tribal nations in South Dakota and the Devil's Lake Sioux tribal nation in North Dakota. From 2001-2003, the study was expanded to include a family cohort to investigate the genetic contributions to cardiovascular disease and its risk factors (Strong Heart Family Study, SHFS). The SHFS included over 3,700 individuals aged at least 15 years from 94 extended families, including over 800 family members of the original SHS cohort.
Study design
Cohort
Number of participants at first data collection
4,549 (SHS participants)
3,776 (SHFS participants)
Age at first data collection
45 - 74 years (SHS participants)
≥ 15 years (SHFS participants)
Participant year of birth
Varied (SHS participants)
Varied (SHFS participants)
Participant sex
All
Representative sample at baseline?
No
Sample features
Country
Year of first data collection
1989
Primary Institutions
University of Oklahoma (OU)
Profile paper DOI
Funders
National Heart, Lung, and Blood Institute (NHLBI)
National Institutes of Health (NIH)
Ongoing?
Yes
Data types collected
- Interview – unspecified
- Physical or biological assessment (e.g. blood, saliva, gait, grip strength, anthropometry)
- Secondary data
- Self-report questionnaire – unspecified
- None
- None
- Healthcare data
- Mortality data
Engagement
Keywords
