The SEED study is a multi-ethnic longitudinal population-based study that evaluates the incidence, prevalence, risk factors, and novel biomarkers of age-related eye diseases for Singaporean adults of Malay, Indian, and Chinese descent. The SEED cohort is based on an age-stratified random sampling strategy of individuals above the age of 40 years from 15 residential districts in the South-Western part of Singapore. A total of just over 10,000 Singaporean adults participated in the baseline SEED examination. The mean age of all baseline participants was 58.9 years, and had almost equal distributions of participants between all three ethnic groups (3,280 Malays, 3,400 Indians, and 3,353 Chinese). There has been a 6-year follow-up (SEED-2) and a 12-year follow-up (SEED-3).
Study design
Cohort
Number of participants at first data collection
10,033 (participants)
Age at first data collection
≥ 40 years (participants)
Participant year of birth
Varied (participants)
Participant sex
All
Representative sample at baseline?
The Singapore population in terms of age, housing, and socio-economic status.
Sample features
Country
Year of first data collection
2004
Primary Institutions
Singapore Eye Research Institute (SERI)
Duke–NUS Medical School (Duke–NUS)
National University of Singapore (NUS)
Links
Profile paper DOI
Funders
Agency for Science, Technology and Research (A*STAR)
National Medical Research Council (NMRC)
Ongoing?
Yes
Data types collected
Engagement
Keywords
Consortia and dataset groups