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Siyakhula Cohort
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Sample details

The Siyakhula Cohort includes over 1,500 human immunodeficiency virus (HIV)-negative children born between 2001 and 2006 to HIV-infected and HIV-uninfected mothers from the Hlabisa sub-district in rural South Africa. Children were enrolled when aged between 7 and 11 years from two sources. Firstly, children were recruited from the Vertical Transmission Study (VTS), a previous early-life breastfeeding intervention study conducted in the sub-district. Secondly, children were recruited from the Africa Centre Demographic Surveillance Area situated in part of the sub-district, as long as they had not previously participated in the VTS. Additionally, some VTS children living in the sub-district but outside of the surveillance area were included in the cohort.

Study design
Cohort

Number of participants at first data collection

1,536 (participants)

Age at first data collection

7 - 11 years (participants)

Participant year of birth

2001 - 2006 (participants)

Participant sex
All

Representative sample at baseline?
No

Sample features

Children and young people
Rural populations
Dataset details

Country

South Africa

Year of first data collection

2012

Primary Institutions

Africa Health Research Institute (AHRI)

Links
No website available

Profile paper DOI

doi.org/10.1093/ije/dyx148

Funders

Grand Challenges Canada

Ongoing?
Yes

Data types collected

mentalHealthData
dataLinkage
Quantitative data collection
  • Computer, paper or task testing (e.g. cognitive testing, theory of mind doll task, attention computer tasks)
  • Interview – face-to-face
  • Physical or biological assessment (e.g. blood, saliva, gait, grip strength, anthropometry)
Qualitative data collection
  • None
Neuroimaging data collection
  • None
Linked or secondary data
  • Existing research data
Features

Engagement

  • None
  • Keywords

    Anthropometry
    Behavioural problems
    Breastfeeding
    Cognition
    Health and wellbeing
    Human immunodeficiency virus (HIV)
    Infant exposures
    Maternal mental health
    Prenatal exposures
    Rural areas

    Consortia and dataset groups

    Collaboration for the Establishment of an African Population Cohorts Consortium (CE-APCC)
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