SJLIFE is a retrospective cohort that was established to follow-up the health of adults treated for cancer during childhood and adolescence. Eligibility criteria for participation in SJLIFE initially includes diagnosis of pediatric cancer treated or followed at St. Jude Children's Research Hospital (SJCRH), attained age of 18 years or older, and survival of 10 or more years from diagnosis. In 2015, eligibility criteria were expanded to include 5-year survivors of any age up to June 30, 2012. Whereas SJLIFE does not specify age at cancer diagnosis, SJCRH generally restricts acceptance to children < 25 years of age at the time of cancer diagnosis. The most common forms of pediatric cancer include leukaemia, lymphoma, and central nervous system malignancy. SJLIFE participants (both in the original and expanded cohorts) are invited to return to SJCRH at least once every 5 years.

Recruitment is ongoing