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Study of Women's Health Across the Nation (SWAN)
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Sample details

The SWAN study is a multi-site longitudinal, epidemiological study designed to examine the health of women during their middle years in the United States of America. The study examines the physical, biological, psychological, and social changes during this transitional period. SWAN participants consist of women aged 42 to 52 years at baseline who had a uterus and at least one intact ovary, reported a menstrual period within the past three months, and had not taken hormone medications in the three months prior. A total of 3,302 women completed the baseline study (1,550 Caucasian, 935 African American, 286 Hispanic, 250 Chinese, and 281 Japanese). As of September 2024, SWAN has completed the screening, baseline, and 16 follow-up visits. Visits have taken place approximately every year.

Study design
Cohort

Number of participants at first data collection

3,302 (participants)

Age at first data collection

42 - 52 years (participants)

Participant year of birth

Varied (participants)

Participant sex
Female

Representative sample at baseline?
No

Sample features

Middle-aged people
Women
Dataset details

Country

United States of America

Year of first data collection

1994

Primary Institutions

Albert Einstein College of Medicine

Massachusetts General Hospital (MGH)

Rush University Medical Center (Rush)

University of California, Davis (UC Davis)

University of California, Los Angeles (UCLA)

Links

swanstudy.org/

Funders

Department of Defense (DoD)

Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

NIH Office of Research on Women's Health (ORWH)

National Center for Complementary and Alternative Medicine

National Institute of Mental Health (NIMH)

Ongoing?
Yes

Data types collected

neuroImagingData
mentalHealthData
Quantitative data collection
  • Activity log (e.g. food, sleep, exercise)
  • Computer, paper or task testing (e.g. cognitive testing, theory of mind doll task, attention computer tasks)
  • Interview – face-to-face
  • Physical or biological assessment (e.g. blood, saliva, gait, grip strength, anthropometry)
  • Self-report questionnaire – paper or computer assisted
  • Wearable devices
Qualitative data collection
  • None
Neuroimaging data collection
  • Magnetic Resonance Imaging (MRI)
Linked or secondary data
  • None
Features

Engagement

  • Patients, service users, lived experience involvement
  • Community engagement
  • Participant or community advisory groups
  • Keywords

    Anthropometry
    Biological determinants
    Biological samples/biospecimens
    Menopause
    Menstruation
    Physical health
    Psychosocial factors
    Women's health
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