T-SOLID is a prospective cohort study based in Taizhou city, China, with an aim to investigate genetic, metabolic, behavioral, and environmental risk factors, and their interplay, for chronic liver diseases (CLDs). Participants were recruited from the Taizhou Longitudinal Study (TZL), and were enrolled from 2018 to 2021. By the end of 2021, a total of over 28,000 participants were enrolled. Passive, registry-based follow-ups are planned to be performed biennially, and patients who regularly consume alcohol and/or are at high risk for CLD are planned to be actively visited every three years. The first, and most recent sweep, was completed in 2021. These follow-ups are ongoing and are planned to be maintained for more than 40 years.
Study design
Cohort
Number of participants at first data collection
28,623 (participants)
Age at first data collection
40 - 70 years (participants)
Participant year of birth
1948 - 1981 (participants)
Participant sex
All
Representative sample at baseline?
Citizens living in Taizhou City, China, that are aged 40 to 70 years old.
Sample features
Country
Year of first data collection
2018
Primary Institutions
Fudan University (复旦大学)
Profile paper DOI
Funders
National Natural Science Foundation of China (国家自然科学基金委员会, NSFC)
Science and Technology Innovation 2030
Shanghai Municipal Science and Technology Major Project
Shanghai Rising-Star Program
Ongoing?
Yes
Data types collected

Engagement
Keywords