TEDDY is a multicentre, international prospective study designed to identify environmental triggers of type 1 diabetes (T1D) in genetically at-risk children from ages 3 months until 15 years. Newborn screening began in September 2004 and was completed in March 2011. There are over 8,600 children enrolled in the 15-year prospective follow-up. There are 12 centres across four countries in Europe (Finland, Germany and Sweden) and the United States of America (Georgia/Florida, Colorado and Washington). Children were followed every 3 months from birth to the age of 4 years. For subjects who seroconvert to positive autoantibodies, the follow-ups continued every 3 months until age 15 years.
Study design
Cohort, Biobank
Number of participants at first data collection
8,677 (participants)
Age at first data collection
0 - 15 years (participants)
Participant year of birth
Varied (participants)
Participant sex
All
Representative sample at baseline?
No
Sample features
Countries
Year of first data collection
2004
Primary Institutions
Augusta University (AU)
Diabetes Research Institute (Institut für Diabetesforschung)
Lund University (Lunds Universitet)
Medical College of Georgia (MCG)
Pacific Northwest Research Institute (PNRI)
Profile paper DOI
Funders
Centers for Disease Control and Prevention (CDC)
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Juvenile Diabetes Research Foundation (now known as Breakthrough T1D)
National Institute of Allergy and Infectious Diseases (NIAID)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Ongoing?
Yes
Data types collected

Engagement
Keywords
Consortia and dataset groups