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The Environmental Determinants of Diabetes in the Young (TEDDY)
The Environmental Determinants of Diabetes in the Young logo
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Sample details

TEDDY is a multicentre, international prospective study designed to identify environmental triggers of type 1 diabetes (T1D) in genetically at-risk children from ages 3 months until 15 years. Newborn screening began in September 2004 and was completed in March 2011. There are over 8,600 children enrolled in the 15-year prospective follow-up. There are 12 centres across four countries in Europe (Finland, Germany and Sweden) and the United States of America (Georgia/Florida, Colorado and Washington). Children were followed every 3 months from birth to the age of 4 years. For subjects who seroconvert to positive autoantibodies, the follow-ups continued every 3 months until age 15 years.

Study design
Cohort, Biobank

Number of participants at first data collection

8,677 (participants)

Age at first data collection

0 - 15 years (participants)

Participant year of birth

Varied (participants)

Participant sex
All

Representative sample at baseline?
No

Sample features

At-risk offspring
Multi-site
Newborns, infants and babies
Dataset details
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Countries

Finland, Germany, Sweden, United States of America

Year of first data collection

2004

Primary Institutions

Augusta University (AU) (Academic, United States of America)

Diabetes Research Institute (Institut für Diabetesforschung) (Research, Germany)

Lund University (Lunds Universitet) (Academic, Sweden)

Medical College of Georgia (MCG) (Academic, United States of America)

Pacific Northwest Research Institute (PNRI) (Research, United States of America)

Links

teddy.epi.usf.edu/

maelstrom-research.org/study/teddy

doi.org/10.1007/s00125-015-3514-y

Profile paper DOI

doi.org/10.1002/dmrr.2427

Funders

Centers for Disease Control and Prevention (CDC) (Government, United States of America)

Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) (Government, United States of America)

Juvenile Diabetes Research Foundation (now known as Breakthrough T1D) (Third Sector, United States of America)

National Institute of Allergy and Infectious Diseases (NIAID) (Government, United States of America)

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) (Government, United States of America)

Ongoing?
Yes

Data types collected

mentalHealthData
Quantitative data collection
  • Interview – online
  • Physical or biological assessment (e.g. blood, saliva, gait, grip strength, anthropometry)
Qualitative data collection
  • None
Neuroimaging data collection
  • None
Linked or secondary data
  • None
Features

Engagement

  • Community engagement
  • Keywords

    Autoimmune disorders
    Celiac disease
    Diabetes
    Environmental determinants
    Genetic predisposition
    Thyroid function

    Consortia and dataset groups

    Swedish Cohort Consortium (Cohorts.se)
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