Themba Lethu Clinical Cohort
The Themba Lethu Clinical Cohort follows patients enrolled in the HIV Care and Treatment program at the Themba Lethu Clinic (TLC) in Johannesburg, Gauteng Province, South Africa. The cohort consists of all patients who have tested positive for the human immunodeficiency virus (HIV) and have ever enrolled for HIV care at the TLC since the national rollout of the anti-retroviral therapy (ART) program in April 2004. As of 2011, the cohort consists of over 8,000 participants in pre-ART care and over 21,000 receiving ART, resulting in a total cohort of over 29,000 patients. As of 2016, the Themba Lethu Clinical Cohort has been incorporated into the Right to Care Clinical HIV Cohort, which includes nine other study sites. Participants are generally followed up every 3 to 6 months.
Study design
Cohort - clinical
Number of participants at first data collection
29,318 (participants as of 2011)
Recruitment is ongoing
Age at first data collection
≥ 18 years (participants)
Participant year of birth
Varied (participants)
Participant sex
All
Representative sample at baseline?
No
Sample features
Country
Year of first data collection
2004
Primary Institutions
Boston University (BU)
Duke University
Themba Lethu Clinic, Helen Joseph Hospital
University of the Witwatersrand, Johannesburg
Profile paper DOI
Funders
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
National Institute of Allergy and Infectious Diseases (NIAID)
President's Emergency Plan for AIDS Relief (PEPFAR)
Right to Care (RTC)
United States Agency for International Development (USAID)
Ongoing?
Yes
Data types collected
- Interview – face-to-face
- Physical or biological assessment (e.g. blood, saliva, gait, grip strength, anthropometry)
- Secondary data
- Self-report questionnaire – paper or computer assisted
- None
- None
- Healthcare data
- Mortality data
Engagement
Keywords
