Tohoku Medical Megabank Project Birth and Three-Generation Cohort Study (TMM BirThree)
The TMM BirThree is a birth and three-generation cohort study focusing on common diseases involving the interplay between genetic and environmental factors in the wake of the Great East Japan Earthquake (GEJE) and the subsequent tsunami. Pregnant women and their families were recruited through clinics and hospitals in the disaster struck area in Miyagi Prefecture, Japan. The cohort consists of over 23,000 newborns and their siblings, parents, grandparents and great-grandparents, resulting in over 70,000 total participants.
Study design
Cohort - birth
Number of participants at first data collection
73,529 (participants)
8,763 (fathers)
22,230 (mothers)
4,276 (maternal grandmothers)
793 (paternal grandfathers)
1,320 (paternal grandmothers)
78 (great-grandparents)
1,474 (extended family members)
9,393 (siblings of newborns)
1,657 (maternal grandfathers)
Age at first data collection
Varied (participants)
Participant year of birth
Varied (participants)
Participant sex
All
Representative sample at baseline?
No
Sample features
Country
Year of first data collection
2013
Primary Institutions
Iwate Medical University (岩手医科大学)
Iwate Tohoku Medical Megabank Organization (IMM)
Tohoku University (東北大学)
Tohoku University Tohoku Medical Megabank Organization (ToMMo)
Profile paper DOI
Funders
Japan Agency for Medical Research and Development (AMED)
Ministry of Education, Culture, Sports, Science and Technology (MEXT/Monbusho)
Reconstruction Agency
Ongoing?
Yes
Data types collected
- Activity log (e.g. food, sleep, exercise)
- Physical or biological assessment (e.g. blood, saliva, gait, grip strength, anthropometry)
- Secondary data
- Self-report questionnaire – online
- Self-report questionnaire – paper or computer assisted
- None
- Magnetic Resonance Imaging (MRI)
- Healthcare data
- Medical birth registry
- Other government data
Engagement
Keywords
Consortia and dataset groups
