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Tokyo Twin Cohort Project (ToTCoP)
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Sample details

ToTCoP investigates human growth and development in a Japanese twin population. The study recruited twins aged from 0 to 2 years from the 252 municipalities in the Tokyo Metropolis and neighbouring Kanagawa, Chiba, and Saitama prefectures. Participants were initially recruited in 2004 through invitation letters and the Basic Resident Register (BRR), focusing on twins residing in these regions. At baseline, 1,619 pairs of twins from 1,601 families were recruited. Follow-ups were conducted annually to track the growth and development of the participants until 2023. Participants of this study are now tracked through the Keio Twin Registry as a sister study hosted by the Keio Twin Research Center (KoTReC).

Study design
Cohort - twin

Number of participants at first data collection

3,238 (participants)

Age at first data collection

0 - 2 years (participants)

Participant year of birth

2004 - 2006 (participants)

Participant sex
All

Representative sample at baseline?
No

Sample features

Dizygotic and monozygotic twins
Newborns, infants and babies
Dataset details

Country

Japan

Year of first data collection

2004

Primary Institutions

Keio Twin Research Center (KoTReC)

Keio University (慶應義塾大学)

Links

totcop.keio.ac.jp/

doi.org/10.1017/thg.2019.109

Funders

Japan Science and Technology Agency (科学技術振興機構, JST)

Ministry of Education, Culture, Sports, Science and Technology (MEXT/Monbusho)

Ongoing?
No

Data types collected

neuroImagingData
mentalHealthData
dataLinkage
Quantitative data collection
  • Computer, paper or task testing (e.g. cognitive testing, theory of mind doll task, attention computer tasks)
  • Interview – face-to-face
  • Physical environment assessment (e.g. pollution, mould)
  • Physical or biological assessment (e.g. blood, saliva, gait, grip strength, anthropometry)
  • Self-report questionnaire – unspecified
Qualitative data collection
  • None
Neuroimaging data collection
  • Electroencephalography (EEG)
  • Near-infrared spectroscopy (NIRS)
Linked or secondary data
  • Other government data
Features

Engagement

  • Community engagement
  • Keywords

    Genetics
    Growth
    Human development
    Mental health
    Neurocognitive development
    Neuroimaging
    Parenting and family
    Sibling relationships
    Stressful life events

    Consortia and dataset groups

    The Keio Twin Research Center (KoTReC)
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