Understanding Pregnancy Signals and Infant Development (UPSIDE)
UPSIDE investigates the pathways by which maternal distress impacts children's physical and neurodevelopment during critical and sensitive periods. From December 2015 to April 2019, women with normal-risk pregnancies were recruited at less than 14 weeks gestation from outpatient obstetric clinics affiliated with the University of Rochester in the United States. Study visits occurred in each trimester and included extensive psychological, sociodemographic, health behaviour, and biospecimen collection. Placenta and cord blood were collected at birth. Child visits occur at birth and at 1, 6, 12, 24, 36, and 48 months of age.
Study design
Cohort - primary caregiver and child, Cohort - birth
Number of participants at first data collection
294 (pregnant women)
277 (children)
Age at first data collection
≥ 18 years (pregnant women)
Birth (children)
Participant year of birth
Varied (pregnant women)
2015 - 2019 (children)
Participant sex
All
Representative sample at baseline?
No
Sample features
Country
Year of first data collection
2015
Primary Institutions
University of Rochester
Profile paper DOI
Funders
National Institutes of Health (NIH)
Ongoing?
Yes
Data types collected
- Computer, paper or task testing (e.g. cognitive testing, theory of mind doll task, attention computer tasks)
- Interview – face-to-face
- Interview – phone
- Physical or biological assessment (e.g. blood, saliva, gait, grip strength, anthropometry)
- Secondary data
- Self-report questionnaire – online
- Ethnography or participant observation
- Electroencephalography (EEG)
- Magnetic Resonance Imaging (MRI)
- Geographic, spatial & environmental data
- Medical birth registry
Engagement
Keywords
Consortia and dataset groups
