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Venda Health Examination of Mothers, Babies and their Environment Study (VHEMBE)
Venda Health Examination of Mothers, Babies and their Environment Study logo
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Sample details

The VHEMBE study investigates the effects of prenatal and childhood exposure to insecticides used to combat malaria in a cohort in Limpopo province in northeastern South Africa. The study recruited pregnant women at least 18 years old in the early labour stages or shortly after delivery from Tshilizidini Hospital in the Vhembe district of South Africa's Limpopo Province. Participants had not been diagnosed with malaria during the pregnancy, lived near the hospital, and spoke Tshivenda at home. At baseline, over 750 pregnant women were recruited into the study resulting in the addition of over 750 babies entering the study at birth. Participants were followed up 1 week postpartum and at 1, 2, 3.5, and 5 years after birth.

Study design
Cohort - primary caregiver and child

Number of participants at first data collection

752 (pregnant women)

752 (babies)

Age at first data collection

≥ 18 years (pregnant women)

Birth (babies)

Participant year of birth

Varied (pregnant women)

2012 - 2013 (babies)

Participant sex
All

Representative sample at baseline?
No

Sample features

Pregnant people
Dataset details

Country

South Africa

Year of first data collection

2012

Primary Institutions

McGill University

University of California, Berkeley (UC Berkeley)

University of Pretoria (Yunibesithi ya Pretoria, Universiteit van Pretoria)

Links

cerch.berkeley.edu/research-programs/vhembe-study

doi.org/10.1111/andr.12235

Funders

Canadian Institutes of Health Research (CIHR, Instituts de recherche en santé du Canada, IRSC)

National Institute of Environmental Health Sciences (NIEHS)

Ongoing?
Yes

Data types collected

dataLinkage
Quantitative data collection
  • Interview – face-to-face
  • Physical environment assessment (e.g. pollution, mould)
  • Physical or biological assessment (e.g. blood, saliva, gait, grip strength, anthropometry)
  • Secondary data
Qualitative data collection
  • None
Neuroimaging data collection
  • None
Linked or secondary data
  • Geographic, spatial & environmental data
Features

Engagement

  • Community engagement
  • Keywords

    Allergies
    Biological samples/biospecimens
    Chemical exposures
    Environmental exposures
    Human development
    Infant biosamples
    Maternal health
    Prenatal exposures
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