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Vertical Transmission Study (VTS)
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Sample details

The VTS aimed to determine the effect of infant feeding practices on human immunodeficiency virus (HIV) infection rates of infants at 6 and 22 weeks of age, and the infant survival rate at 24 months of age, according to feeding practices and HIV status. From 2001, over 3,400 HIV-infected and -uninfected pregnant women and almost 3,000 of their infants were recruited from KwaZulu-Natal and Durban in South Africa. All pregnant women were tested for HIV and counselled on infant feeding options. The pregnant women were assessed from the antenatal period to 2 years post-partum, and their children were assessed from birth to 2 years of age until 2006.

Study design
Cohort, Cohort - birth, Cohort - primary caregiver and child, Cohort - clinical

Number of participants at first data collection

3,445 (pregnant women)

2,938 (infants)

Age at first data collection

≥ 16 years (pregnant women)

Birth (infants)

Participant year of birth

Varied (pregnant women)

No information available (infants)

Participant sex
All

Representative sample at baseline?
No

Sample features

Mother and child dyad
Newborns, infants and babies
People living with HIV
Pregnant people
Dataset details

Country

South Africa

Year of first data collection

2001

Primary Institutions

University of KwaZulu-Natal (INyuvesi yakwaZulu-Natali, UKZN)

Links
No website available

Profile paper DOI

doi.org/10.1093/ije/dyp165

Funders

Wellcome Trust

Ongoing?
No

Data types collected

dataLinkage
Quantitative data collection
  • Activity log (e.g. food, sleep, exercise)
  • Interview – face-to-face
  • Physical or biological assessment (e.g. blood, saliva, gait, grip strength, anthropometry)
  • Secondary data
Qualitative data collection
  • None
Neuroimaging data collection
  • None
Linked or secondary data
  • Medical birth registry
Features

Engagement

  • None
  • Keywords

    Anthropometry
    Biological samples/biospecimens
    Birth records and measurement
    Breastfeeding
    Feeding behaviour
    Growth
    Hospital admissions
    Human development
    Human immunodeficiency virus (HIV)
    Infant biosamples
    Medical history
    Morbidity and mortality
    Pregnancy
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