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Women's Health Initiative Observational Study (WHI OS)
Women's Health Initiative Observational Study logo
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Sample details

The WHI OS was established to explore the predictors and natural history of important causes of morbidity and mortality in postmenopausal women, and to serve as a secular control for the WHI Clinical Trial (CT). It enrolled over 93,000 postmenopausal women between the ages of 50 to 79 years at 40 clinical centres across the United States of America. Baseline assessment was conducted from 1994 to 1998. Participants were followed up annually for 8 to 12 years, including in-person clinical assessments and mailed questionnaires.

Study design
Cohort

Number of participants at first data collection

93,676 (participants)

Age at first data collection

50 - 79 years (participants)

Participant year of birth

Varied (participants)

Participant sex
Female

Representative sample at baseline?
No

Sample features

Middle-aged people
Older and elderly people
Postmenopausal
Women
Dataset details

Country

United States of America

Year of first data collection

1994

Primary Institutions

Fred Hutch Cancer Center

National Heart, Lung, and Blood Institute (NHLBI)

Links

whi.org/

doi.org/10.1016/S0197-2456(97)00078-0

nhlbi.nih.gov/science/womens-health-initiative-whi

ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi

Funders

National Heart, Lung, and Blood Institute (NHLBI)

National Institutes of Health (NIH)

Ongoing?
No

Data types collected

mentalHealthData
Quantitative data collection
  • Interview – face-to-face
  • Interview – phone
  • Physical or biological assessment (e.g. blood, saliva, gait, grip strength, anthropometry)
  • Self-report questionnaire – paper or computer assisted
Qualitative data collection
  • None
Neuroimaging data collection
  • None
Linked or secondary data
  • None
Features

Engagement

  • Community engagement
  • Keywords

    Biological samples/biospecimens
    Bone density
    Diet and nutrition
    Health and wellbeing
    Morbidity and mortality
    Older women
    Osteoporosis
    Post-menopausal
    Psychosocial factors
    Women's health
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