Wisconsin Infant Study Cohort (WISC)
The WISC began in 2013 comparing immune responses in cord blood from healthy babies born into farming environments and those born into non-farming environments. Pregnant women were identified and recruited through Marshfield Clinic Health System (MCHS), which covers a primarily rural area of Wisconsin, United States of America. A total of 240 pregnant women were enrolled into the study in 2013. Approximately half of the participants were classed as 'Farm mothers', meaning they live on or within an eighth of a mile of a farm, or work on or live with someone who works on a farm. The families completed their first questionnaire before birth, then were followed up nine times before the child turned 24 months.
Study design
Cohort - primary caregiver and child
Number of participants at first data collection
240 (mother and child dyads)
Age at first data collection
≥ 18 years (mothers)
Birth (children)
Participant year of birth
Varied (mothers)
2013 - 2018 (children)
Participant sex
All
Representative sample at baseline?
No
Sample features
Country
Year of first data collection
2013
Primary Institutions
University of Wisconsin-Madison
Profile paper DOI
Funders
Marshfield Clinic Health System Foundation
NIH National Institute of Allergy and Infectious Diseases (NIH-NIAID)
National Center for Advancing Translational Sciences (NCATS)
Ongoing?
Yes
Data types collected
- Physical environment assessment (e.g. pollution, mould)
- Physical or biological assessment (e.g. blood, saliva, gait, grip strength, anthropometry)
- Secondary data
- Self-report questionnaire – paper or computer assisted
- None
- None
- Healthcare data
Engagement
Keywords
Consortia and dataset groups
