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Workpackage 5 of the Innovative Medicines Initiative Pharma-Cog (WP5 IMI Pharma-Cog)
Workpackage 5 of the Innovative Medicines Initiative Pharma-Cog logo
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The WP5 IMI Pharma-Cog project aimed to test the value and utility of computerized cognitive markers and biomarkers in the multi-modal characterization of prodromal Alzheimer’s Disease patients with amnesic mild cognitive impairment (aMCI). Between December 2011 and June 2013, around 150 aMCI patients were enrolled in 13 European memory clinics across the Netherlands, Spain, Germany, Italy, Greece, and France. Participants were followed up 6, 12, 18, 24, 3,0, and 36 months after baseline. This study is a part of the European Alzheimer's Disease Neuroimaging Initiative (E-ADNI).

Study design
Cohort

Number of participants at first data collection

147 (participants)

Age at first data collection

55 - 90 years (participants)

Participant year of birth

Varied (participants)

Participant sex
All

Representative sample at baseline?
No

Sample features

Multi-site
Older and elderly people
People with mild and major neurocognitive disorders
Dataset details
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Countries

Denmark, France, Germany, Italy, Netherlands

Year of first data collection

2009

Primary Institutions

Innovative Medicines Initiative (IMI)

Links

kb.imi-neuronet.org/admin/projects/25

alz.org/research/for_researchers/partnerships/wwadni/european_adni

kb.imi-neuronet.org/admin/projects/25

Profile paper DOI

doi.org/10.1111/joim.12482

Funders

European Union (EU)

Innovative Medicines Initiative (IMI)

Ministry of Economy, Finance and Industry (Ministère de l'Économie, des finances et de l'industrie, MEFI)

Ongoing?
No

Data types collected

neuroImagingData
mentalHealthData
Quantitative data collection
  • Computer, paper or task testing (e.g. cognitive testing, theory of mind doll task, attention computer tasks)
  • Interview – unspecified
  • Physical or biological assessment (e.g. blood, saliva, gait, grip strength, anthropometry)
  • Self-report questionnaire – unspecified
Qualitative data collection
  • None
Neuroimaging data collection
  • Diffusion Tensor Imaging (DTI)
  • Electroencephalography (EEG)
  • Functional magnetic resonance imaging (fMRI)
  • Magnetic Resonance Imaging (MRI)
Linked or secondary data
  • None
Features

Engagement

  • None
  • Keywords

    Alzheimer's disease (AD)
    Dementia
    Genetics
    Magnetic Resonance Imaging (MRI)
    Mild cognitive impairment (MCI)
    Neuroimaging

    Consortia and dataset groups

    ADataViewer
    European Alzheimer's Disease Neuroimaging Initiative (E-ADNI)
    World Wide Alzheimer's Disease Neuroimaging Initiative (WW-ADNI)
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