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Wisconsin Registry for Alzheimer’s Prevention (WRAP)
Wisconsin Registry for Alzheimer’s Prevention logo
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Sample details

WRAP is a longitudinal observational cohort of over 1,700 adults in Wisconsin, United States of America, recruited between the ages of 40 and 65 from 2001 onwards. The cohort is enriched with participants at risk for Alzheimer's disease, defined as having at least one biological parent diagnosed with dementia due to probable Alzheimer's disease. Several recruitment sources were utilised, such as memory assessment clinics, newspaper advertisements, and word of mouth.

Study design
Registry, Cohort

Number of participants at first data collection

452 (paticipants)

Recruitment is ongoing

Age at first data collection

40 - 65 years (participants)

Participant year of birth

Varied (participants)

Participant sex
All

Representative sample at baseline?
No

Sample features

Middle-aged people
Registry
Dataset details

Country

United States of America

Year of first data collection

2001

Primary Institutions

University of Wisconsin-Madison

Links

wrap.wisc.edu/

dss.niagads.org/cohorts/wisconsin-registry-for-alzheimers-prevention-wrap/

doi.org/10.1016%2Fj.dadm.2017.11.007

Profile paper DOI
Not available

Funders

Alzheimer's Association

Extendicare Foundation

National Institutes of Health (NIH)

North-western Mutual Life Foundation

Wisconsin Alzheimer's Institute

Ongoing?
Yes

Data types collected

neuroImagingData
mentalHealthData
Quantitative data collection
  • Computer, paper or task testing (e.g. cognitive testing, theory of mind doll task, attention computer tasks)
  • Physical or biological assessment (e.g. blood, saliva, gait, grip strength, anthropometry)
  • Self-report questionnaire – unspecified
Qualitative data collection
  • None
Neuroimaging data collection
  • Magnetic Resonance Imaging (MRI)
  • Positron Emission Tomography (PET)
Linked or secondary data
  • None
Features

Engagement

  • Community engagement
  • Keywords

    Alzheimer's disease (AD)
    Biological samples/biospecimens
    Biomarkers
    Cognitive assessments
    Dementia
    Disease prevention
    Epidemiology
    Family health history
    Genetic predisposition
    Sub-studies

    Consortia and dataset groups

    Global Alzheimer’s Association Interactive Network (GAAIN)
    Image and Data Archive (IDA)
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